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Enhanced Apollo X CHO Clone Screening with Targeted Locus Amplification
FUJIFILM Diosynth Biotechnologies has integrated Cergentis’s Targeted Locus Amplification (TLA) technology into Apollo X cell line development as a powerful tool for completely sequencing transgenes and integration sites.Highlights
- TLA detects all single-nucleotide variants (SNVs) and structural variants in an integrated transgene sequence.
- TLA analyses can be used in development and quality control of cell lines, for clone selection, and for assessment of clonality and genetic stability.
![Application note - Application of TLA for enhanced CHO clone screening Application note - Application of TLA for enhanced CHO clone screening](https://download.cergentis.com/hs-fs/hubfs/Fujifilm%20appnote%20front%202021.png?width=250&height=307&name=Fujifilm%20appnote%20front%202021.png)