Enhanced Apollo X CHO Clone Screening with Targeted Locus Amplification
FUJIFILM Diosynth Biotechnologies has integrated Cergentis’s Targeted Locus Amplification (TLA) technology into Apollo X cell line development as a powerful tool for completely sequencing transgenes and integration sites.Highlights
- TLA detects all single-nucleotide variants (SNVs) and structural variants in an integrated transgene sequence.
- TLA analyses can be used in development and quality control of cell lines, for clone selection, and for assessment of clonality and genetic stability.