APPLICATION NOTE

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Enhanced Apollo X CHO Clone Screening with Targeted Locus Amplification

FUJIFILM Diosynth Biotechnologies has integrated Cergentis’s Targeted Locus Amplification (TLA) technology into Apollo X cell line development as a powerful tool for completely sequencing transgenes and integration sites.

 

Highlights

  • TLA detects all single-nucleotide variants (SNVs) and structural variants in an integrated transgene sequence.
  • TLA analyses can be used in development and quality control of cell lines, for clone selection, and for assessment of clonality and genetic stability.
Application note - Application of TLA for enhanced CHO clone screening

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